Oct
26
bone pain and prostate cancer
October 26, 2009 | Leave a Comment
The treatment of Vitamin D deficiency can improve the treatment of prostate cancer bone pain and muscle power.
Veldhuizen etc Ⅱ has completed a period of clinical studies to determine whether the supplement of Vitamin D( VitD) could ease the bone metastasis of bone pain and improve muscle.
Included in the study of hormone therapy of 16 cases of patients with adanced prostate cancer, after four weeks after the placebo treatment, accept VitD 2000U/oral, 12 weeks.
At the beginning of the study, and every four weeks after 1 times pain questionnaire and muscle testing. Every examination are determined VitD and serum calcium concentration. Results showed that 16 cases (44 percent), 7 cases of low concentration. VitD baseline By using VitD treatment, 4 patients (25%) pain score improved, 6 patients (37%) muscle strengthening.
Pain score improvement and subjective symptoms related to the conventional arrangement, but no significant analgesic requirements.
Researchers think that, in not sensitive to hormones, the prostate cancer VitD occurred the lack of significant proportion. In this part, VitD may be added to relieve pain, enhance strength and improve the quality of life of a useful adjunctive treatment.
In addition Clodronate can relieve the pain of prostate cancer.
About four days after the treatment we can observe analgesic effect. Patients from 45% to Karnofsky average index to 70 per cent. Researchers believe that USES of two phosphate treatment painful bone metastasis and mitoxantrone torre anthraquinone (dragon) and the prednisone is equivalent treatment.
Researchers say that with 21 cases, there is no reaction in 9 cases are due to appear extends into soft tissue or oppressive nerve bone metastasis, the other is due to exist widely in 9 cases bone metastasis and Karnofsky index below 30%.
Heidenreich doctor thinks, when men appear prostate specific antigen after castrated asymptomatic rises, we should use two phosphate to prevent bone formation in the lesion.
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